Refaquin cream is a medication used for the short-term treatment of moderate to severe facial melasma. Refaquin contains hydroquinone, tretinoin, and fluocinolone acetonide. Hydroquinone ydroquinone produces reversible depigmentation of the skin by inhibiting the enzymatic oxidation of tyrosine to 3,4-dihydroxyphenylalanine (dopa) and suppressing other melanocyte metabolic processes. Tretinoin is classified therapeutically as a keratolytic. Fluocinolone acetonide is a synthetic corticosteroid drug derived from hydrocortisone.
General Indication :
Short term therapy for moderate to severe Melasma.